Nikon CoolscanThis is a scan of a slide mounted in glass from 1945. There is no way to remove the crud which is sandwiched in the slide without breaking the glass. But, below, you can see how the Coolscan improves things by scanning the slide after clicking on two boxes to activate Digital ICE (scratch and dust "removing") processing and color restoration processing.
For more examples of images processed by the Coolscan, go here.
For an excellent review of the newer model Coolscan LS 5000, go here.